All posts by Turacoz Group

World Osteoporosis Day-October 20, 2016

“Love Your Bones and Protect Your Future”

World Osteoporosis Day is observed every year on October 20, with a year-long campaign to raise global awareness on the prevention, diagnosis and treatment of osteoporosis and metabolic bone diseases. Organized by the International Osteoporosis Foundation (IOF) every year, the campaign aims to promote awareness about the disease and its associated risk factors. It encourages high-risk individuals to become proactive about their own bone health and advocate for a worldwide preventive care.

Osteoporosis: The Disease

Osteoporosis is a disease characterized by decreased bone mass and deterioration of the bone tissue, leading to an increased risk of fracture. It causes a net loss of bone strength; as a result, even a slight bump or fall can lead to a broken bone (referred to as a fragility fracture). Osteoporosis affects all bones in the body; however, fractures occur most frequently in the vertebrae (spine), wrist, and hip. Osteoporotic fractures may also occur in the pelvis, upper arm and lower leg. Osteoporosis itself is not painful but the broken bones can result in severe pain,major physical disability and sometimes, complete immobility.

Signs and Symptoms

  • Bone pain or tenderness
  • Fractures with minimum or no trauma
  • Loss of height with time and age
  • Neck or lower back pain
  • Stooped posture

 

Risk Factors

Modifiable Risk Factors Non-Modifiable Risk Factors
Smoking Family history
Alcohol consumption Previous fracture
Low body mass index Certain medications (glucocorticoids, immunosuppressants, steroids etc.)
Poor nutrition Primary/secondary hypogonadism in men
Vitamin D deficiency Menopause/hysterectomy
Frequent falls Certain medical disorders (HIV, rheumatoid arthritis, chronic kidney disease, malignancy etc.)
Insufficient exercise
Eating disorders (anorexia and bulimia)
Sedentary lifestyle

 

Treatment Options for Osteoporosis

Goals of osteoporosis treatment includes pain management, stopping or slowing down bone loss, preventing bone fractures, and minimizing the risk of falls.

 

Treatment

Non-pharmacological options Pharmacological Options
Calcium supplementation Hormone replacement therapy
Vitamin D supplementation Selective estrogen receptor modulators
Exercise Calcitonin
Surgical intervention Bisphosphonates

 

Preventive Measures

Proper nutrition with regular weight-bearing and resistance exercises are very crucial in protecting bone and muscle health, irrespective of age. Every individual must proactively try to identify their personal risk factors and seek early diagnosis and treatment. Lifestyle modification and medical assistance together could significantly reduce the likelihood for future fractures in osteoporotic patients and give them a better quality of life.

 

Food for Healthy Bones

It’s very important to include adequate daily amounts of calcium, vitamin D, phosphorus, and magnesium for good bone health. These vitamins and minerals are the most important in building bones and teeth. Examples include:

  • ¾ Dairy products (low-fat milk, yogurt and cheese)
  • ¾ Fish
  • ¾ Green vegetables
  • ¾ Fruits
  • ¾ Fortified foods (soy milk, rice milk, breakfast cereals, and breads)

Dietary supplements of calcium and vitamin D might be needed,if our diet does not provide us with the required minimum dose.

Though our genes are responsible for our skeletal properties like body height and bone strength, we can positively influence our bone health by incorporating certain lifestyle changes (diet and exercise) and becoming actively involved in monitoring the early signs of osteoporosis.

So much we ignore our bone health and intake of nutritious diet,that we forget that deficiency of calcium and vitamin D may lead to osteoporosis and serious fractures. The disease osteoporosis is not gender-specific; both men and women are affected by its painful consequences. Turacoz Healthcare Solutions supports the cause of healthy bones and tells you about the osteoporosis. So, learn to love your bones and protect your future. On World Osteoporosis Day, let’s join in to know more about your bone health.Include healthy food in your diet and say cheers to the healthy bones!

Desktop Workers! Eat it Right!

Desktop dining has now become a common phenomenon with approximately 65% of working professionals typically having lunch at their desks on a regular basis. Pizzas, burgers, sandwiches, muffins, momos, and doughnuts are the most preferred meals of this group of busy workers who generally, in order to clock-in extra working hours, avoid extra spends and get hooked to these high fat, sugar and salt diets because of lack of options. This increasing trend of consuming quick-tasty-junk at desk when combined with compulsive snacking, caffeine overdose, and minimal water intake plays a massive havoc on our body.

This unhealthy food habit in sedentary office life is a risk factor for several lifestyle diseases such as:

  • Obesity
  • Cardiovascular diseases
  • Stroke
  • Lipid disorders
  • Depression
  • Anxiety

Since our body switches-off the fat-burning process when sitting for a longer period of time, we really need to mind the calories and correct our eating habits while at work.Though we require less calories during this period of minimal physical activity, our body needs a well-balanced and proper nutritional diet to function optimally and prevent malnutrition.

The initial area of focus should be on giving our diet a complete makeover by planning in advance for healthy meals and snack options for the entire week. This proactive planning would limit our urge of compulsive binging and thus,help in controlling the habit of going for unhealthy meal options.

Foods to Include in Daily Diet:

  • Complex carbohydrates (whole grains, cereals, pulses, beans, legumes, fruits, vegetables etc.)
  • Good protein sources (eggs, lean meat, poultry without skin, fish and low fat dairy products)
  • Healthy forms of fat (yogurt, cheese, skimmed milk, nuts, olive oil etc.)
  • Dietary fibers and nutrients (dry fruits, sunflower and pumpkin seeds, granola bars etc.)
  • Sufficient quantity of water

Foods to Avoid in Daily Diet:

  • Processed foods (white flour bread and pastas, chips, candies, processed meat, canned food etc.)
  • Food with high-cholesterol content (egg yolk, bacon, butter, seafood, red meat, sausages, cheese, cakes, pies, and cookies)
  • Unhealthy fat (foods rich in saturated fats like beef, lamb, pork, coconut oil, palm oil etc.)
  • Empty calories (foods with no nutritional content like sweets, soft drinks, and high fat salad dressings)

A nutritious and balanced meal gives us a sustained energy flow and optimizes brain oxygen level without getting too hard on our digestive system. This provides fuel to our brain and energy to our body, improves our cognition, and helps us stay focused – all of which increase our productivity and performance at work.

Turacoz Healthcare Solutions understands the need to make smarter diet choices while sitting for longer working hours. We aim to increase awareness about the negative health impact of unhealthy eating and suggest the ways to healthy eating. Let’s improve our eating quotient and make the right choice.

Breast Cancer: Early Detection Saves Life

October is the “Breast Cancer Awareness Month”. Breast cancer is the second most common cause of death due to cancer in women, after lung cancer. Lately, there has been an increase in the incidence of breast cancer in the developing world, owing to increase in life expectancy, urbanization and adoption of western lifestyle.

Some Statistical Facts about Breast Cancer

According to the World Health Organization (WHO),

  • Breast cancer is the most common cancer in women, both in the developed and the less developed countries
  • Over 508, 000 women died due to breast cancerin 2011
  • 58% of breast cancer deaths occur in less developed countries
  • Incidence rates are quite high in non-Hispanic white women
  • Asian/Pacific Islander women have the lowest incidence and death rates due to breast cancer

Symptoms of Breast Cancer

There are no specific symptoms when the tumor is small. Therefore, it is very important for women to follow recommended screening guidelines for detecting breast cancer at an early stage. When breast cancer has grown to a large size, it can be felt as a painless lump.Breast cancer can spread to underarm lymph nodes and cause a lump or swelling. Less common signs and symptoms include:

  • Breast pain or heaviness
  • Persistent changes to the breast, such as swelling, thickening, or redness of the breast’s skin
  • Abnormal discharge from nipple

Prevention of Breast Cancer

The American Cancer Society has recommended guidelines for Nutrition and Physical Activity for Cancer Prevention. They can be enlisted as:

  • Achieve and maintain a healthy weight throughout life.
    • Be fit throughout life without being underweight.
    • Avoid excess weight gain at all ages.
    • Do regular physical activity and limit the intake of high-calorie foods and drinks.
  • Adopt a physically active lifestyle.
    • Adults should doat least 150 minutes of moderate-intensity or 75 minutes of vigorous-intensity activity each week.
    • Children and adolescents should performat least 1 hour of moderate- or vigorous activity each day.
    • Limit the sedentary behavior such as sitting, lying down, watching television, and other forms of screen-based entertainment.
  • Follow a healthy diet, with an emphasis on plant foods.
    • Choose foods and beverages in amounts that help achieve and maintain a healthy weight.
    • Reduce the consumption of processed meat and red meat.
    • Eat at least 2½ cups of vegetables and fruits each day.
    • Choose whole grains over refined-grain products.
  • Avoid drinking alcoholic beverages.
    • Limit to no more than 1 drink (per day) for women or 2 (per day) for men.

Approximately,eight out of ten women develop malignant lumps in the breast. Therefore, don’t underestimate the importance of a monthly breast self-exam. Breast cancer can be fatal at any age. Women should therefore undergo proper counseling and screening for early detection. Turacoz Healthcare Solutions (THS) aims to raise awareness about the breast cancer. We, as a medical writing company in Delhi, consider it our corporate responsibility to share the healthcare measures for prevention of breast cancer.

 

World Heart Day-September 29, 2016 : Your Heart says, “Listen to the Murmurs!”

Cardiovascular diseases (CVDs) are a group of disorders of the heart and the blood vessels which include coronary heart disease, cerebrovascular disease, peripheral arterial disease, ischemic heart disease, rheumatic heart disease, congenital heart disease, raised blood pressure, deep vein thrombosis, pulmonary embolism, and heart failure. The usual acute events are heart attack and stroke that are mainly caused by the blockage due to fatty-acid deposition which prevents the blood from flowing to the heart or brain.

Disease burden

  • Globally, CVDs are the prime cause of death
  • Around 17.5 million people died from CVDs in 2012
  • Around 7.4 million deaths were due to coronary heart disease only
  • More than half of the CVD deaths take place in low- and middle-income countries

Causes

Cardiovascular diseases may be caused due one or more of the following factors:

  • Tobacco and/or alcohol consumption
  • Unhealthy diet
  • Obesity
  • Physical inactivity
  • Hypertension
  • Diabetes
  • Dyslipidemia

Symptoms

A person experiencing any cardiovascular disease can be noted with the symptoms like:

  • Pain/discomfort in the centre of the chest(in case ofheart attack)
  • Discomfort in the arms, left shoulder, elbows, jaw, or back
  • Sudden weakness of the face, most often on one side of the body (in case of stroke)
  • Difficulty in walking, speech, or vision
  • Shortness of breath, fatigue, irregular heartbeats and chest pain (in case of rheumatic heart disease)
  • Light-headednessor severe headache
  • Cold sweating

Prevention

Thomas Fuller once said, “He who cures a disease may be the ‘skill-fullest’, but he who prevents it is the safest physician.”

Some precautionary measures and effective healthcare can definitely help in preventing the CVDs. Here are listed some healthcare measures that one should take to reduce the risk of cardiovascular problems:

  • Abstain from tobacco use
  • Reduce harmful consumption of alcohol
  • Cut down the intake of salt in diet
  • Include 5 servings of fruits and vegetables in daily diet
  • Exercise for 30 minutes every day
  • Get yourself checked for blood pressure, blood cholesterol and blood sugar (diabetes) every three months

Preventive measures suggested by the World Health Organisation include:

  • Comprehensive tobacco control policies
  • Taxation on foods that are high in fat, sugar and salt
  • Campaigns to encourage physical activities such as walking and cycling
  • Regulations to reduce the consumption of alcohol
  • Healthy school meals for children

Individual healthcare interventions targeted to those at high cardiovascular risks

Your heart is at the heart of your health. Together with the World Heart Federation, Turacoz Healthcare Solutions (THS) raises awareness about the CVDs and wants to make you understand what you can do to fuel your heart and give power to your life. You ought to give your heart the care it deserves. So eat healthy, reduce alcohol and tobacco consumption, and keep your heart healthy. Being involved in the medical writing services, THS provides assistance in publication writing, clinical research and regulatory writing, medico-marketing writing, and support for conducting medical advisory board meetings.

 

World Rabies Day, 28th Sep 2016 : Educate. Vaccinate. Eliminate.

This year marks the 10th World Rabies Day, which has become a global phenomenon since its beginning in the year 2007. The theme of this year is: “Educate. Vaccinate. Eliminate.” which emphasizes on the two important actions that we need to take to prevent rabies. Also, the theme reflects the global target of eliminating deaths due to canine rabies by 2030.

Rabies is a viral disease in mammals that is transmitted through the bite of a rabid animal and infects the central nervous system (CNS). Its symptoms range from fever, headache, and general weakness to insomnia, anxiety, confusion, hallucinations, agitation, and difficulty in swallowing. Once clinical signs and symptoms appear, the disease is nearly fatal and the patient can be given only supportive treatment. Thus, it is very important to prevent the disease. Rightly said, prevention is better than cure and after all, prevention is the only remedy for this deadly disease.

KEY FACTS BY WORLD HEALTH ORGANIZATION

·         Dogs contribute to 99% of all the rabies transmissions to humans

·         Rabies causes tens of thousands of deaths every year, majorly in Asia and Africa

·         40% of people bitten by suspected rabid animals are below 15 years of age

·         More than 15 million people get post-bite vaccinations globally, every year

 

Preventing rabies

Rabies can be easily prevented by vaccination. Following measures can help in easy eradication of the disease:

  • Vaccinating dogs to eliminate rabies.
  • Pre-exposure immunization in people, especially those involved in high risk occupations like laboratory workers dealing with animals, children etc.
  • Post-exposure prophylaxis immediately after exposure to rabies can prevent the infection from entering the CNS. This can be done via:
    • Local treatment of the bitten area/wound immediately after exposure
    • Administration of potent rabies vaccines
    • Administration of rabies immunoglobulin, if needed

Turacoz Healthcare Solutions, a medical writing company, aims to spread awareness about the rabies and ways to prevention, in order to help attain the global target of attaining ZERO deaths due to canine rabies by 2030. We offer services to healthcare professionals in publications writing, clinical research and regulatory writing, medico-marketing writing, and support for medical advisory board meetings. We aim to provide health solutions for everyone to live a happy and healthy life.

Turacoz Healthcare Solutions opens its new WING in Pune

Turacoz is a medical communications company providing customized and cost-effective solutions to healthcare and pharma industries. The team of young, dynamic, and energetic professionals contribute to the core service spectrum, which includes publication writing;

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Importance of Macro-Editing in Medical Writing

Editing is an important task that is performed by an editor with a good scientific background and good editing skills. Once a manuscript is finalized, it is reviewed for editorial concerns. It includes checking the content or the information in order to ensure that the thoughts or concepts are expressed clearly and in a logical way to form a comprehensive and meaningful information on the whole. Editing requires critical thinking and careful analysis of the information. It is broadly divided into micro- and macro-editing.

Micro-editing deals with the technical aspects and ensures the language and style are correct and consistent. On the other hand, macro-editing ensures transparency, accuracy, and consistency of the information in the document. Following things are generally rectified during macro-editing :

  1. Logical flow of story from one paragraph to the next
  2. Clarity and completeness of the information
  3. Clearly mentioned rationale/purpose of the document
  4. Information is oriented towards the target reader
  5. Accuracy of data
  6. Tables and figures are cited appropriately in the document
  7. Supportive references are accurate and mentioned appropriately in the text
  8. Conclusions are succinctly summarized
  9. Other things that are taken care during editing include sentence structure, repetitiveness of information, language style (tone and voice), parallelism in the statements, paragraph structure, and word and phrases usage with proper meaning depending on the context

The best way for macro-editing is that the writer self-checks the document based on the below-mentioned questions:

  • Is the introductory paragraph clear enough to indicate the purpose and provide a broad outline of the content?
  • Is every statement relevant to the purpose of the study, with no deviations?
  • Does the text flow reasonably from one paragraph to the next paragraph?
  • Are the sentence structures and language varied enough, without too much repetition?
  • Are the evidences or references given to statements appropriate?
  • Is the terminology consistent throughout the text, or if more than one term has been used to refer to something, is it clear that they are one and the same thing?
  • Is the language and tone appropriate for the reader?
  • Does the information provided in the document meet the readers’ needs?
  • Are the conclusions clearly and effectively summarized?
  • Is the content in the draft aligned as per the journal or congress guidelines?
  • Are the page, text, tables, figures, references, and other information formatted as per the style sheet?

Turacoz Healthcare Solutions (THS) shares the importance of macro-editing in medical writing. Being a medical writing company, Turacoz is involved in publication writing, training solutions, and skill development program. We offer medical writing solutions at par with the latest trends in journal-publication.

Role of a Medical Writer in Advisory Board Meetings

Medical writing is a multidimensional profession which requires creating numerous scientific/non-scientific documents for various phases of a drug life-cycle. Different types of documents prepared by a medical writer are later utilized by the pharmaceutical companies in procuring approval from the regulatory bodies and for knowledge sharing with the healthcare stakeholders. These documents may include (but are not limited to) documents for pre-clinical studies, clinical trials, and post-marketing studies,reports of advisory board meetings, patient educational material, and promotional material. Among all the above-mentioned documents, writing reports for advisory board meetings is an integral part of the medical writing profession.

What is an Advisory Board?

Advisory boards are considered as an important tool for understanding the unmet medical or healthcare needs of a drug/product. By forming an ‘advisory board’, the pharmaceutical companies or medical societies aim to engage their key opinion leaders (KOLs)in order to get better insights on the various medical benefits/limitations of their products from the medical fraternity. Productive discussions held during the advisory board meetings are used to gather visions on possible research opportunities, including guidance on the clinical development and trial protocols, as well as unmet health care needs of current clinical practices that might drive future clinical strategies. The organizing body usually involves a medical writer during an advisory board meeting for capturingevery detail of the discussion held at the medical advisory board meeting and later drafting an objective-driven report which is shared at different knowledge sharing platforms.

What is the Role of a Medical Writer?

The responsibility and role of a medical writer vary according to the objective of the advisory board and according to the type of report required by the organizing body. This may include:engaging KOLs for an advisory board, preparing questionnaires, conducting online surveys (for understanding unmet needs), preparing a pre-meeting report to be shared with KOLs, preparing presentations for the advisory board meeting, hosting an advisory board, capturing minutes of meeting, preparing draft for meeting report, and modifying the report into a publication-ready literature. Hence, it is very important that a medical writer has a prior understanding of the objective of the meeting and nature of deliverable.

Turacoz Healthcare Solutions provides end-to-end support for conducting an advisory board and preparing high-quality scientific reports of the meeting. We have successfully conducted several national and global advisory boards related to preclinical research and product positioning in the past two years and look forward to partnerships in future. Turacoz has experienced medical writers who understand the requirements of our clients and efficiently capture the body and soul of an advisory board meeting.

Triclosan and Memory Loss in Children

What is Triclosan?

Triclosan is commonly used as a disinfectant or an antiseptic to reduce and control the bacterial contamination. It is an organic compound with a slight phenolic smell. It is a very well-known biocide for over 40 years. Although its main application is in cosmetics (maximum allowed concentration 0.3%), triclosan is also ubiquitously usedinanti-bacterial soaps and toothpastes (even upto the concentration0.46%). About 75% of liquid anti-bacterial soaps and 30% of bars use triclosan as an active ingredient. The drug, which was originally used strictly in hospitals and healthcare centres, was adopted by manufacturers of soaps and other home products in course of time.

Triclosan Causes Memory Loss

Triclosan is believed to cause endocrine disruption; even low levels of triclosan may disrupt thyroid function. Poor thyroid function, in turn, may lead to depression, weight gain, fatigue, and memory loss. Also, triclosan degrades to dioxins in the body, which can destroy brain cells. As a result, neurological disorders and emotional distress might happen.

Triclosan attaches itself to the receptor molecules on the surface of brain cells and leads to increased calcium levels inside the cells. As a result, cells become over-excited, leading to cellular death. Over-excitation of brain cells may lead to developmental delays and autism in children.

The United States Food and Drug Administration (US FDA) research, along with countless independent studies, have shown that triclosan does not provide any health benefits as compared to the old-fashioned soaps. Using triclosan-containing anti-bacterial soaps does not give any added advantage over triclosan-free normal soaps in providing antimicrobial protection.

The U.S. FDA has issued a proposed rule requesting additional scientific data to support the safety and effectiveness of such active ingredients used in topical antiseptic rubs (including hand sanitizers) marketed over-the-counter (OTC).

How to Reduce Exposure to Triclosan

Anti-bacterial soaps and hand-sanitizers mostly contain triclosan, which is harmful for children. However, you must ensure that children clean theirhands before eating. A few tips can help you to avoid exposure to triclosan:

  • Choose a safer soap or liquid hand soaps which do not contain triclosan.
  • Encourage washing hands with soap and water, the best way to reduce the number of microbes in most of the situations.
  • If soap and water are not available, use an alcohol-based hand sanitizer that contains at least 60% alcohol.

Exposure to triclosan can disrupt normal brain function and cause memory loss in children. We, at Turacoz Healthcare Solutions, consider it our corporate social responsibility to raise awareness for the minimal use of triclosan-containing antibacterial hand sanitizers, especially in children. Protect your children from the toxic effects of triclosan.

Health Hazards of Being a Medical Writer

Being a medical writer has a lot of allure, particularly if you are having a flexible work schedule, competitive salary package, and assured growth as a professional. However, having these advantages doesn’t insulate you from some of the hazards that you may face as a medical writer. Medical writing, being a sedentary job, requires sitting behind a desk for long hours, which over a period of time can take a toll on your health.

The Risks

  • Metabolic Diseases 
    Medical writers spend their maximum awake time sitting and working. Sedentary lifestyle and reduced physical activity contribute to the excessive body fat around the waist and abnormal cholesterol levels, which are major risk factors for certain diseases like obesity, hypertension, and diabetes.
  • Cardiovascular Diseases
    The sedentary lifestyle attributes to abnormal cholesterol level which is a major risk factor for cardiovascular diseases like atherosclerosis, stroke, angina, and heart attack. It is found that the risk of heart disease is increased by 50 per cent in a sedentary worker (who sits for 11 hours or more a day) even if exercise is performed regularly.
  • Posture Problems
    Due to the nature of work, a medical writer usually works in a ‘static posture’ throughout the day that results in a faulty ergonomics. Rotator cuff disease, chronic pain in the neck, shoulder, back or hand, ruptured disks, and pulled or strained muscles/ligaments are the few disorders that might occur due to static posture. Several studies have reported that there is an increased risk of physical injuries if a worker maintains a static posture throughout working hours.
  • Bone and Joint Disorders
    Spending daily 8 hours or more working on a desktop/laptop without any significant movement of the joints and muscles of limbs may result in loss of muscle mass, loss of muscular flexibility, carpal tunnel syndrome, and hand/wrist tendinitis.
  • Eye Problems
    Prolonged working on a desktop or laptop and gazing the screen for hours expose eyes to undue effects of brightness of the screen that later results in eye strain, temporary blurred vision, headaches, and migraines.
  • Psychological Problems
    In today’s competitive world, analogous to any other professional, medical writers also experience several psychological problems like stress, anxiety, exhaustion, depression, and disordered sleep.

 

The Remedies

Overall, being more physically active is the basic remedy to reduce the chances of all the potential health problems that are associated with the sedentary nature of the work of a medical writer. It is recommended that a sedentary worker (e.g. a medical writer) should spend a minimum of 10 minutes in moderate- or vigorous-intensity aerobic exercise to improve circulation of blood and burn calories. Additionally, there are a few health tips which a medical writer should follow:

  • Take regular breaks during the working hours. After every couple of hours, stand up from the desk and move around.
  • After every 30 minutes of desktop work, do basic stretching exercises at your desk. This will help in maintaining flexibility of the muscles.
  • Avoid getting locked into a static posture. Change your posture frequently by adjusting the angles of your hips, knees, ankles, and elbows while sitting.
  • Be more active: take stairs instead of the lift, prefer public transport or cycle to work.
  • Eat smart. Avoid binging and unhealthy eating habits.
  • Keep your body well hydrated by drinking enough amount of water.
  • Don’t eat while you work. Ensure you eat lunch away from your desk.
  • Adjust the brightness of the screen of your laptop/desktop. Don’t gaze the screen fora long Take regular breaks to relax your eyes.
  • Ensure that you spend at least an hour each week in outdoor sport or leisure activity of your choice.
  • Don’t work hard, work smart.Plan well before you start to work, divide all major tasks into sub-tasks and organise your work schedule. This will help to reduce the chances of having stress and anxiety.
  • Don’t be a workaholic! Make sure you spend a reasonable amount of time with your family and friends, which is important for your mental and emotional well being.

Being sedentary is the root-cause of most of the health problems. Making appropriate lifestyle changes in your daily work schedule may reduce your risk of having these health problems. As a medical communication company, we at Turacoz Healthcare Solutions always encourage our medical writers and everyone to exercise daily and lead a physically active, healthy life.